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6 days ago These mutations are also called germline mutations because they are present in the parent's egg or sperm cells, which are also called germ.

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14 Dec Mutations that occur in the germ line — the cells that develop into sperm or eggs — can be passed on to the next generation and, perhaps.

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Description:I haven't gone through the full paper, but on brief perusal it looks like most of the real hard data they have is of environment-induced epigenetic changes that actually gets somehow sensed by the mate and is avoided. The reason why I'm skeptical about de novo mutations is the funny way evolution seems to work in complex organisms like us: Most genetic change seems to begin as polymorphisms that gets established in the population and then the polymorphisms that are better suited to handle some environmental insults are selected for more than the polymorphisms that don't handle some problems well. Thats why almost all genetic complications we see and hear of in human populations are very precisely defined and consistently keep recurring Which should not be the case if purely random mutations were causing them.

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