Lidocaine and tissue penetration
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Dermal and underlying tissue pharmacokinetics of lidocaine after topical application.
The deep-tissue penetration of lidocaine below a dermally applied site was quantified in a rat model. The concentrations of lidocaine in tissues below the.
The effect of protein binding on the deep tissue penetration and efflux of dermally applied salicylic acid, lidocaine and diazepam in the perfused rat hindlimb.
Description:This was a prospective study with sequential allocation depending on the response of previous patient Dixon and Massey's up-down method involving 25 patients submitted to spinal blocks with 25G Quincke needle. Time elapsed between the end of infiltration and 25G Quincke needle puncture was established in logarithmic scale. Initial interval was 30 seconds.
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Date: 2018-08-18
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